CARIM Newsletter November 2022

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This newsletter contains information on the following subjects:
  • CARIM Symposium 2022
  • Virchow Prize Arina ten Cate-Hoek
  • Pélerìn award Floor Pinckaers
  • Opening AMICARE
  • Awards ARTERY 22 conference
  • Vacancy CARIM EPC
  • Launch UMployee
  • Willem's Wisdoms
  • Blog FAIR principles
  • Call for supervisors BMS course
  • Paramount Papers
  • Cardiovascular Grand Rounds Maastricht
  • Who's New?!
  • Academic Events
  • Lectures, symposia & events
  • Media Moments

CARIM newsletter

Contributions for the newsletter (e.g. news of events and grants, important publications, societial impact related topics and research results related to CARIM's research) can be sent to Please submit the text in English and include a short title. The text should be max. 200 words. If applicable, include high resolution pictures and other documents.

CARIM Symposium 2022

The annual CARIM Symposium 2022 will take place on Wednesday 16 November 2022.
During our annual Symposium, CARIM researchers will present their work by giving a lecture or presenting a poster. Furthermore, Prof. Marie-José Goumans (UMC Leiden) will give a lecture during the ReGEN/iPSC session.
This year's traditional Robert Reneman CARIM Lecture will be given by Prof. Peter Stenvinkel, professor and senior lecturer at Department of Renal Medicine of Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden. 

The symposium will be held at the Minderbroedersberg, followed by a festive evening at Thiessen.

Click here to register for the event. 


Virchow Prize Arina ten Cate-Hoek

On Thursday 13 October, in honour of World Thrombosis Day, Dr Arina ten Cate-Hoek (Dept. of Internal Medicine) received the Virchow Prize 2022. The prize was awarded by the DGA (Deutsche Gesellschaft für angiologie , Gesellschaft für Gefäßmedizin), the joint professional association for angiologists, phlebologists and vascular surgeons of the 3 German-speaking countries (Germany, Austria, and Switzerland). She receives the prize for her scientific work in the field of Post Thrombotic Syndrome and in particular for research into the effectiveness of compression therapy and the direct impact of her work on various guidelines.

Since 2015, the Virchow Prize has been awarded annually to a scientist with special merit. The aim of the prize is to raise awareness of thrombosis and pulmonary embolism, their complications and consequences, and the possibilities of early diagnosis. Both the population and the medical world must be made more aware of this problem. The prize is awarded for special publications, health care studies, applications and measures to support the implementation of guidelines. The prize is not open to the public. The award is presented once a year on World Thrombosis Day - always on 13 October.

Prof.dr. J. Terpstra Award 2022 Philippe Vangrieken

Dr Philippe Vangrieken (Dept. of Internal Medicine) received the Prof.Dr. J. Terpstra Award 2022 during the annual Dutch diabetes symposium. The main objective of this prize is to stimulate young researchers who conduct research in the field of diabetes mellitus. The Prof.dr J. Terpstra Young Investigator Award amounts to 10,000 Euros. The winner will also receive a matching memento with inscription.

Pélerìn award Floor Pinckaers

Floor Pinckaers (Dept. of Neurology) has received this year's Pélerìn award for her research on dual-energy CT after endovascular stroke treatment. The award was presented during the annual Pélerìn Symposium that took place on 5 October 2023. The annual Pélerìn physician assistants symposium is the ideal opportunity for physician assistants, physician researchers and semi-doctors to draw attention to scientific research carried out from Maastricht UMC+.



Thursday 20 October, AMICARE, Aachen-Maastricht Institute for Cardiorenal Disease, was opened in Aachen. In this research institute, researchers from Maastricht UMC+ and RWTH Aachen University work together to unravel the relationship between heart and vascular problems and kidney disease. It is one of the first European institutes in which researchers from different countries from different disciplines will collaborate so intensively on this medically urgent problem.

The research institute focuses on translational research that aims to translate fundamental research results into applications for the patient. This means that on the one hand the researchers will continue to investigate the mechanisms and causes of the convergence of heart, vessel and kidney problems. On the other hand, the scientists also expect to be able to accelerate research into the early recognition and treatment of this syndrome with AMICARE, for example with medication.

PhD candidates from Maastricht University winning two awards during the ARTERY 22 conference

19-22 October 2022, PhD candidates from Maastricht University attended conference ARTERY22 in Nancy, France. They went there with a total of 7 colleagues, who all presented work about their current research in cardiovascular disease. They were in a winning mood, two of them got rewarded. Berta Ganizada is a shared PhD candidate from Cardiothoracic surgery and Biochemistry department, where she is working under supervision of Prof. Leon Schurgers, Dr Koen Reesink, Dr Elham Bidar and Prof. Jos Maessen. During ARTERY22, she got the opportunity to give an oral presentation on her current work on 'Histomorphometric analysis of cell and matrix components of ascending thoracic aortic aneurysm'. The aim of this project is to identify an early-stage screening markers for patients with thoracic aortic aneurysm. During ARTERY22 congress, she got rewarded with the second place Young Investigator Award.

Cindy van Loo is a PhD candidate in the department of Biomedical Engineering under supervision of Dr Bart Spronck and Prof. Leon Schurgers and Prof. Tammo Delhaas. Here, she investigates the effect of vasoconstriction on vascular stiffness. During the same conference in Nancy, she got rewarded with a Research Exchange Grant for her research proposal in collaboration with the lab of Jason Au at the University of Waterloo in Canada! This enables her to investigate the mechanical properties of aortic and carotid artery tissue of human donors.


Vacancy CARIM Educational Programme Committee

The CARIM Educational Programme Committee (EPC) has a vacancy for a CARIM staff member from January 2023 onwards. We are looking for a new member with experience with supervision of PhD candidates.

The EPC focusses on the quality of the CARIM PhD Programme. The committee consists of 4 CARIM staff members and PhD representatives from I’M CARIM.
The committee meets on a monthly basis.

If you are interested, you can contact one of the present staff members in the committee: Boy Houben, Matthijs Blankesteijn or Eline Kooi before the end of November.

Launch UMployee

On 8 November we are launching our new employee intranet: UMployee! At the moment, you get information through several channels. Starting 8 November, UMployee will be your digital start of the day. You can easily keep up to date with the latest news and find all the information you need in one central place.

As a result, the familiar Communication and Executive Board e-mails will disappear. Many newsletters will also disappear, and UM news will become a student-only mailing. This will streamline our internal communication.

Intranet belongs to us all
UMployee becomes a source of information: here you will find everything you need. We will also share news, updates and useful links in relevant groups. We will add you automatically to the group of your faculty or service centre, but you know best which news is most relevant to you. So, starting 8 November, join other groups and follow what you find interesting: then you won’t miss a thing!

We’ll be in touch!
In addition, you can share information yourself on UMployee in groups: we will tell you more about that later. You will be able to communicate with colleagues and respond to messages on the intranet. This way, we’ll find each other both on campus and online. Do you want colleagues to be able to find you easily and know when you are at work? Then complete your personal profile with practical information, such as tasks, areas of expertise and useful information about (home) working days.

Tuesday 8 November: a day to celebrate
On November 8, we’re celebrating UMployee going live. And we’ll do so in multiple places. Do you want to know where and how? Get in touch with the community manager of your faculty or service centre for more information!

Willem's wisdoms

Maastricht University profiles itself as the most European university in the Netherlands. Looking at the international composition of students and staff, the size of the university and the income from all European funds, this is correct.

A blog shows an analysis of the EU research and innovation Framework Programme Horizon 2020 (2014-2020), in particular the position of Maastricht University as a Dutch participant, its partners and the EU keywords that characterise the university as a participant. Click here for the full blog.

How to use the FAIR principles in data management? Read this blog!

How do you make sure your data comply with the FAIR principles of Findability, Accessibility, Interoperability and Reusability? Open Science ambassador Dennie Hebels (MERLN) kicks off the blog series on scientific integrity with a blog on data management.
From the moment you plan your experiment all the way to the endpoint of analysing your results and writing them down, a researcher should always have data management in mind. Good data management ensures that data is and remains accessible to you and to other researchers.
Read more in the blog 'Data management and data practices':

Call for supervisors Core of Biomedical Science course 

During the Core of Biomedical Science course, students get the opportunity to work in one of a research lab of the Maastricht University and MUMC+ This part of the course is dedicated to learning basic principles, opportunities and challenges of techniques/methods/skills that will contribute to the development towards an investigator.

For 6 weeks (2-3 days/week) the students should be immersed in a research environment where they will have the opportunity to interact with research teams and learn from experts in various fields of the biomedical area (e.g. oncology, cardiovascular, neurosciences, metabolism, bioinformatics, genetics, imaging). At the end of the course, students demonstrate their work with a skills video clip.

If you are interested to contribute to the course as a project supervisor, please feel free to submit a project using this template. More details on the content, planning and hour compensation can be found here.

Paramount Papers

Intravital microscopy for real-time monitoring of drug delivery and nanobiological processes

Intravital microscopy (IVM) expands our understanding of cellular and molecular processes, with applications ranging from fundamental biology to (patho)physiology and immunology, as well as from drug delivery to drug processing and drug efficacy testing. In this review, we highlight modalities, methods and model organisms that make up today’s IVM landscape, and we present how IVM - via its high spatiotemporal resolution - enables analysis of metabolites, small molecules, nanoparticles, immune cells, and the (tumor) tissue microenvironment. We furthermore present examples of how IVM facilitates the elucidation of nanomedicine kinetics and targeting mechanisms, as well as of biological processes such as immune cell death, host-pathogen interactions, metabolic states, and disease progression. We conclude by discussing the prospects of IVM clinical translation and examining the integration of machine learning in future IVM practice.

Momoh J, Kapsokalyvas D, Vogt M, Hak S, Kiessling F, van Zandvoort M, Lammers T, Sofias AM. Intravital microscopy for real-time monitoring of drug delivery and nanobiological processes. Adv Drug Deliv Rev. 2022 Oct;189:114528. doi: 10.1016/j.addr.2022.114528. Epub 2022 Sep 5. PMID: 36067968.

Click here for the full publication.

Cardiovascular Grand Rounds Maastricht

4 November - Tobias Petzold (MD, PhD), Ludwig- Maximilians- University of Munich, Germany
'Megakaryocytes, a new player in cardiovascular diseases'

18 November - Vimal Karani (PhD) University of Reading, UK
'Nutrigenetics and precision nutrition for the prevention of cardiometabolic diseases'

8.00-9.00 AM online and on-site

ZOOM-link for all meetings:
Meeting ID: 972 2487 2025
Password: 678252

Click here for the upcoming lectures.

The steering committee for the Cardiovascular Grand Rounds consists of CARIM staff members of the 3 divisions (Heart, Vessels and Blood) and includes Renske Olie, Sébastien Foulquier, Pieter Goossens, Jordi Heijman, Rory Koenen, Blanche Schroen, Julie Staals and Kristiaan Wouters. If you have suggestions for a specific topic or speaker, please contact any of the committee members and they will assist in scheduling the lecture with you.

Who's New?!

Academic Events

PhD conferral Laura Willemsen, 10 November, 13.00 hours, MBB 4-6
Supervisor: Prof. J.M. ten Berg
Co-supervisor: Dr C.M. Hackeng
Title: Thrombosis and Hemostasis in Coronary Artery Bypass Grafting Surgery

PhD conferral Anne Tavenier, 17 November, 16.00 hours, MBB 4-6
Supervisors: Prof. A.W.J. van 't Hof, Prof. J.M. ten Berg
Co-supervisors: Dr R.S. Hermanides (Isala Zwolle), Dr J.P. Ottervanger (Isala Zwolle)
Title: Towards optimal platelet inhibition and pain relief in STelevation myocardial infarction

PhD conferral Dawid Kaczor, 28 November, 13.00 hours, online
Supervisors: Prof. T.M. Hackeng, Dr R.R. Koenen
Co-supervisor: Prof. R. Kramann
Title: Inflammatory actions of chemokines and extracellular versicles in pathological tissue remodeling

Lectures, symposia & events

Microscopy Autumn School 2022 - 7-11 November 2022
FEM keynote series: Elke van Hoof - 8 November 2022
FAIR Coffee Lecture: “Open Access strategies and licensing of publications” - 9 November 2022

CARIM Symposium - 16 November 2022
NLSEV - 17 & 18 November 2022
Patient engagement in drug development: moving beyond tools and standardization? - 18 November 2022
Webinar Spectrum of Innovation: Chromium, Visium, Xenium - 21 November 2022

Vascular Rounds | Hypertensie: intensief en invasief - 22 November 2022
Young@Heart event 'Career Perspectives in and outside academia: What is your next step?' - 25 November 2022
Night of Science - 8 December 2022
FEM book launch of "De Nee Club" | "The No Club" - 12 December 2022

Upcoming School Council meetings:

KNAW agenda
Brightlands news

Media Moments 7/10 Het team van Frits Prinzen (CARIM) heeft, samen met wetenschappers van King’s College in Londen, aan de wieg gestaan van een app die door de microfoon van de smartphone tegen de borst te houden niet alleen het hartritme kan horen, maar ook het geluid van de hartkleppen. Op die manier kan de app, met de naam Echoes, in de toekomst wellicht door dokters gebruikt worden om hartpatiënten op afstand te monitoren. De Britse krant Daily Mail schrijft er uitgebreid over. 1/10 Rob Holtackers (CARIM) bedacht tijdens een borrel een eenvoudige manier om kleine littekens in het hart van bloed te onderscheiden op MRI-scans. Ziekenhuizen over de hele wereld passen inmiddels dagelijks zijn nieuwe scanmethode toe. Afgelopen voorjaar promoveerde hij cum laude op zijn onderzoek naar de nieuwe techniek. In de rubriek Jong Geleerd voor het wetenschapskatern van NRC Handelsblad vertelt hij uitgebreid over zijn vinding. 22/10 Wereldwijd komt zwangerschapsvergiftiging steeds vaker voor. Hoewel de meeste klachten na de bevalling verdwijnen, laat deze aandoening bij een deel van de vrouwen verraderlijke sporen achter in het hart én in de hersenen. Chahinda Ghossein-Doha (CARIM) geeft tekst en uitleg in een artikel voor (de website van) het tijdschrift LINDA.

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